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D-Cycloserine

D-Cycloserine

品 牌 MCE
C A S 号 68-41-7
货 号 HY-B0030
规 格 100mg
价 格(元) 420.00
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货号 规格 价格
HY-B0030 100mg 420.00
HY-B0030 500mg 850.00

产品说明


D-Cycloserine (D-环丝氨酸) 是D型丙氨酸类似物。



D-Cycloserine的生物活性


D-Cycloserine is an analog of the amino acid D-alanine.
Target: Antibacterial
D-Cycloserine selectively potentiated the duration of motor cortical excitability enhancements induced by anodal tDCS. D-Cycloserine alone did not modulate excitability [1]. Participants receiving d-cycloserine in addition to exposure therapy reported significantly less social anxiety compared with patients receiving exposure therapy plus placebo. Controlled effect sizes were in the medium to large range [2]. Chronic D-cycloserine significantly reduced nicotine self-administration selectively in rats with low baseline nicotine use, but was ineffective with the rats with higher levels of baseline nicotine self-administration [3].

化学信息


分子量 102.09 储存条件 参考CoA中推荐的条件进行储存。
分子式 C₃H₆N₂O₂
CAS号 68-41-7
溶剂/溶解度 DMSO: ≤ 1 mg/mL (Need warming)

相关文献


[1]. Nitsche, M.A., et al., Consolidation of human motor cortical neuroplasticity by D-cycloserine. Neuropsychopharmacology, 2004. 29(8): p. 1573-8.

[2]. Hofmann, S.G., et al., Augmentation of exposure therapy with D-cycloserine for social anxiety disorder. Arch Gen Psychiatry, 2006. 63(3): p. 298-304.

[3]. Levin, E.D., et al., D-cycloserine selectively decreases nicotine self-administration in rats with low baseline levels of response. Pharmacol Biochem Behav, 2011. 98(2): p. 210-4.